Your Doctor Said Your Cholesterol Is "Borderline." Here's What That Word Is Really Asking You.
Your annual check-up came back and your GP said your cholesterol is "borderline." It's not high enough for a prescription conversation, but it's not low enough to forget about either. For many adults over 40, this is when they start looking for a sensible, natural first step to support healthy cholesterol levels. Red yeast rice is one of the most researched natural ingredients for cholesterol support. Here's the science behind how Eu Yan Sang has refined it in CholesFREE Plus with Natto.
Old Ingredient, New Understanding
Red yeast rice isn't new. It was first recorded around 800 A.D. and valued in Traditional Chinese Medicine for supporting digestion and blood flow. What's new is that modern science can now explain what makes it work, and why the way it's made matters so much.
The Science Behind the Formula
Rice fermented with Monascus purpureus
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Monacolins form naturally during fermentation
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ZEROTOX® reduces impurities and retains active compounds
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Fermented natto adds nattokinase
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One capsule, two complementary actions
Step 1
Where Your Cholesterol Really Comes From
Most of the cholesterol in your body isn't eaten. Your body makes it, mainly in the liver. That's why a borderline result can happen even when you eat well. When red yeast rice ferments, it naturally produces compounds called monacolins. The main one, monacolin K, has the same chemical structure as lovastatin and works on the same pathway the body uses to produce cholesterol. This is the science behind red yeast rice's role in helping maintain healthy cholesterol levels.
Step 2
Why Not All Red Yeast Rice Is Equal
Fermentation is a living process, so results vary. When researchers at the University of Pennsylvania tested 12 red yeast rice supplements, the amount of monacolins ranged widely from one brand to the next. Four of the products also contained raised levels of citrinin, an unwanted fermentation by-product. European regulators now set strict limits on citrinin in red yeast rice supplements. In other words, the label "red yeast rice" tells you very little about what's actually in the capsule.

Laboratory research into red yeast rice behind CholesFREE Plus with Natto.
Step 3
How ZEROTOX® Changes the Result
ZEROTOX® is a patented preparation technique developed with Nanyang Polytechnic researchers. It does two jobs at once. It reduces impurities that arise during fermentation and removes compounds that may result in herb-drug interactions. At the same time, HPLC testing confirms the active compounds are retained. The result is a purer red yeast rice at 620mg per capsule.
Step 4
Why Natto Completes the Formula
Cholesterol is only half the story. The other half is the blood vessels that carry it. Natto is a traditional Japanese food made from fermented soybean, and it helps support healthy blood vessels. During fermentation, natto produces nattokinase, a natural enzyme that researchers have studied for its effects on blood flow. Each capsule contains 30mg of fermented natto, with nattokinase at 20,000 FU/g.
Why Two Ingredients Instead of One
Red Yeast Rice, 620mg (ZEROTOX® purified)
Works where most cholesterol is made. Helps maintain healthy cholesterol levels.
Natto, 30mg
Works on the vessels that carry it. Helps support healthy blood vessels.
Together they support a healthy cardiovascular system and promote healthy blood circulation.
The Eu Yan Sang Difference
Since 1879, Eu Yan Sang has combined the wisdom of Traditional Chinese Medicine with modern research, quality standards and manufacturing practices.
- Red yeast rice purified with patented ZEROTOX® technology
- HPLC testing to confirm active compounds are retained
- Fermented natto to help support healthy blood vessels
- Natural, vegetarian friendly and free from preservatives
Frequently Asked Questions
How do I take CholesFREE Plus?
Take 1 to 2 capsules twice daily after meals, with lukewarm water.
Is red yeast rice the same as a statin?
No. Red yeast rice is a fermented food that naturally contains monacolins, including monacolin K. Because monacolin K shares its structure with lovastatin, stop taking the product and speak with your doctor if you notice muscle aches or weakness.
Can I take it with other medication?
Speak with your doctor first if you take cholesterol-lowering or blood-thinning medicine. Natto contains nattokinase, which may cause bleeding when taken with blood-thinning medication. CholesFREE Plus isn't recommended during pregnancy or breastfeeding, for anyone under 18, for anyone with a history of liver disease, or around surgery.
Take Charge of Your Cholesterol Health
Start your natural cholesterol support routine today!
Try CholesFREE Plus with NattoTraditional Chinese Medicine concepts described in this article reflect traditional TCM theory and usage. They should not be interpreted as modern biomedical claims. Ingredient information is provided for educational purposes and is not intended to diagnose, treat, cure or prevent any disease. Always read the label and follow the directions for use. If symptoms persist, talk to your health professional. This supplement should not replace a balanced diet or any medication prescribed by your doctor.
